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Updated: Jul 16, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
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一个酶激活的光探针用于向瘤成像

Mako Kamiya1, Hisataka Kobayashi, Yukihiro Hama

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|March 14, 2007
PubMed
概括

一个新的光探测器AM-TG-betaGal,可以在体内对β-galactosidase活性进行敏感的光学成像. 这种记者酶成像策略成功地可视化了小鼠中的小瘤,为腹腔镜手术等临床应用提供了潜力.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...