亚酸盐驱动的厌氧甲氧化是由氧性细菌进行的
Katharina F Ettwig1, Margaret K Butler, Denis Le Paslier
1Radboud University Nijmegen, IWWR, Department of Microbiology, Heyendaalseweg 135, 6525 AJ, Nijmegen, The Netherlands. k.ettwig@science.ru.nl
Nature
|March 26, 2010
概括
一种新的无氧甲氧化细菌通过新的代谢途径产生氧气. 这一发现揭示了以前未知的氧气来源,可能会影响早期地球.
科学领域:
- 微生物学 微生物学
- 生物地质化学生物地质化学
- 进化生物学 进化生物学
背景情况:
- 氧气生产主要与光合作用,酸盐呼吸和活性氧物种排毒有关.
- 一个显著的淡水甲沉仍然在生物化学上无法解释.
- 厌氧甲氧化在全球生物地化学循环中的作用至关重要.
研究的目的:
- 确定和描述一种新的氧气生产生物途径.
- 为了阐明一个鲜为人知的淡水甲沉背后的生化机制.
- 探索早期氧气可用性的进化影响.
主要方法:
- 无氧丰富培养物的元基因组测序.
- 主导性细菌"Candidatus Methylomirabilis oxyfera"的全基因组组合. 这种细菌是最常见的.
- 同位素标记实验用于追踪代谢途径.
主要成果:
- 在"Candidatus Methylomirabilis oxyfera"中发现了第四条氧气生产途径.
- 这种细菌通过氧化氧化氧化氧化氧化氧化氧化氧化氧化氧化氧的氧化甲.
- 生物体利用有氧甲氧化途径无氧化,缺乏已知的二生产基因.
结论:
- 已经确定了一种新的生化途径来产生氧气.
- 这一途径解释了大量的淡水甲沉没,并影响了碳化合物的降解.
- 在氧光合作用之前,可能已经有氧气用于微生物代谢.
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