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相关概念视频

Levels of Organization01:09

Levels of Organization

Biological organization is the classification of biological structures, ranging from atoms at the bottom of the hierarchy to the Earth's biosphere. Each level of the hierarchy represents an increase in complexity that builds upon the previous level.Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules comprise...
What are Cells?01:07

What are Cells?

Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.Basic Characteristics of CellsA living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.Furthermore, a living cell possesses genetic information...
Assembly of Complex Microtubule Structures01:32

Assembly of Complex Microtubule Structures

Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
What are Cells?01:15

What are Cells?

Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium, or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
Structural Organization of the Human Body: An Overview01:18

Structural Organization of the Human Body: An Overview

It is convenient to consider the body's structures in terms of fundamental levels of organization that increase in complexity: subatomic particles, atoms, molecules, organelles, cells, tissues, organs, organ systems, and organisms.
To study the chemical level of organization, scientists consider the simplest building blocks of matter: subatomic particles, atoms, and molecules. All matter in the universe is composed of one or more unique pure substances called elements, familiar examples of...
Cell Diversity01:13

Cell Diversity

The concept of a cell started with microscopic observations of dead cork tissue by Robert Hooke in 1665. Hooke coined the term "cell" based on the resemblance of the small subdivisions in the cork to the rooms that monks inhabited, called cells. About ten years later, Antonie van Leeuwenhoek became the first person to observe the living and moving cells under a microscope. In the century that followed, the theory that cells represented the basic unit of life developed.
Multicellular organisms...

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Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair
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从单细胞分析中重建复杂组织.

Lu Wen1, Fuchou Tang1

  • 1Biodynamic Optical Imaging Center, College of Life Sciences, Peking University, Beijing 100871, China.

Cell
|May 13, 2014
PubMed
概括
此摘要是机器生成的。

研究人员分析了单个小鼠耳囊细胞中的基因表达. 这种单细胞基因表达概况提供了对发育和疾病遗传调节的新见解.

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科学领域:

  • 发展生物学 发展生物学
  • 基因组学就是基因组学.
  • 细胞生物学 细胞生物学

背景情况:

  • 单细胞分析技术正在快速发展.
  • 这些方法为研究发育和疾病中的遗传调节提供了机会.

研究的目的:

  • 分析小鼠耳囊中单细胞水平上的基因表达.
  • 了解复杂的3D结构中发育的遗传调节.

主要方法:

  • 单细胞基因表达特征分析.
  • 分析小鼠耳囊,一个高度组织的三维结构.

主要成果:

  • 详细的基因表达模式被确定在单细胞水平在小鼠的耳囊.
  • 这项研究提供了细胞异质性的高分辨率视图.

结论:

  • 对小鼠耳囊单细胞分析为了解发育过程提供了有价值的数据.
  • 这种方法可以揭示发育和疾病的遗传基础.