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相关概念视频

Parental Care00:55

Parental Care

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Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Fertilization01:38

Fertilization

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During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
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Relationship with Parents: Attachment01:28

Relationship with Parents: Attachment

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Parent-child interactions lay the foundation for how we understand relationships throughout life. These interactions are not uniform across families; instead, they are shaped by a range of environmental, emotional, and behavioral factors unique to each caregiver-child dynamic. Social psychologists study these early relationships to understand how patterns formed in infancy influence social functioning and interpersonal behavior in adulthood.Attachment Theory and Early Relational ModelsJohn...
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Development of the Oral Microbiota01:28

Development of the Oral Microbiota

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The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Imprinting01:22

Imprinting

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Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
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相关实验视频

Updated: Apr 25, 2026

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
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Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

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在受孕之前的育儿.

Michelle Lane1, Rebecca L Robker1, Sarah A Robertson2

  • 1The Robinson Research Institute and School of Paediatrics and Reproductive Health, The University of Adelaide, Level 3, Medical School, South Adelaide, SA, 5005 Australia.

Science (New York, N.Y.)
|August 16, 2014
PubMed
概括
此摘要是机器生成的。

父母的年龄和环境暴露通过基因组和表观基因组信息影响胚胎发育. 这些因素,包括DNA甲基化和非编码RNA,影响孩子的终身健康,从怀孕前开始.

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Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period
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Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
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科学领域:

  • 生殖生物学 生殖生物学
  • 发展生物学 发展生物学
  • 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.

背景情况:

  • 受精建立了胚胎基因组蓝图,受父母年龄和环境的影响.
  • 父母的历史和经验通过超越DNA序列的表观遗传信息影响后代.

研究的目的:

  • 探索父母表观遗传信息在编程胚胎和胎儿发育中的作用.
  • 了解跨代表观遗传效应如何影响儿童终身健康结果.

主要方法:

  • 关于父母对后代表观遗传学影响的最新研究的综述.
  • 对精子和卵细胞细胞酸甲基化,染色质模式,非编码RNA和线粒体的变异进行分析.

主要成果:

  • 父母的表观遗传因素,包括甲基化和非编码RNA,被传递给胚胎.
  • 这些跨代表观遗传效应与受孕条件相互作用,对程序开发产生影响.

结论:

  • 父母的表观遗传信息显著影响胎儿发育和终身健康.
  • 生物学家长在受孕之前就开始了,挑战了关于产前发育的传统观念.