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蛋白质组学. 蛋白质组学. 人类蛋白质组的基于组织的地图

Mathias Uhlén1, Linn Fagerberg2, Björn M Hallström3

  • 1Science for Life Laboratory, KTH-Royal Institute of Technology, SE-171 21 Stockholm, Sweden. Department of Proteomics, KTH-Royal Institute of Technology, SE-106 91 Stockholm, Sweden. Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK-2970 Hørsholm, Denmark. mathias.uhlen@scilifelab.se.

Science (New York, N.Y.)
|January 24, 2015
PubMed
概括

这项研究绘制了人体组织蛋白质组的地图,揭示了32个器官的蛋白质表达. 这些发现通过全面的交互式数据库增强了对人类生物学和疾病的理解.

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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