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Updated: Apr 15, 2026

Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads
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MAP4K4调节整合素-FERM结合,以控制内皮细胞的运动性.

Philip Vitorino1, Stacey Yeung1, Ailey Crow1

  • 1Molecular Biology Department, Genentech, Inc., South San Francisco, California 94080, USA.

Nature
|March 25, 2015
PubMed
概括

涉及MAP4K4的新型分子通路,莫因,塔林和β1-整合素对于内皮细胞迁移和膜收缩至关重要. 这条通路调节细胞运动和血管形成,提供了潜在的治疗点.

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