Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Polytene Chromosomes02:04

Polytene Chromosomes

3.6K
3.6K
DNA Microarrays02:34

DNA Microarrays

22.5K
Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
22.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Programmable artificial RNA condensates in mammalian cells.

Nature nanotechnology·2026
Same author

Systematic mapping of emergent transcriptional states in interacting single-cell dyads by Cell-Cell-seq.

bioRxiv : the preprint server for biology·2026
Same author

Modeling cell-cell interactions to advance drug discovery in Idiopathic Pulmonary Fibrosis.

bioRxiv : the preprint server for biology·2026
Same author

Programmable artificial RNA condensates in mammalian cells.

bioRxiv : the preprint server for biology·2026
Same author

TFAP2A+ embryonic progenitor cells undergo fate diversification to give rise to human amnion, germline, and mesoderm.

bioRxiv : the preprint server for biology·2025
Same author

Regenerative Immunotherapy for Cancer: Transcription Factor Reprogramming of Tumor-Specific T Cells.

Cancers·2025
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
查看所有相关文章

相关实验视频

Updated: Mar 21, 2026

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation
12:09

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation

Published on: August 10, 2022

7.6K

人类早期发展的翻译百科全书

Anna Sahakyan1, Kathrin Plath1

  • 1David Geffen School of Medicine, Department of Biological Chemistry, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, Jonsson Comprehensive Cancer Center, UCLA Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Cell
|May 7, 2016
PubMed
概括
此摘要是机器生成的。

研究人员分析单个人类胚胎以了解早期发育. 这项研究揭示了在小鼠模型中未见的人类植入前发育的独特特征.

更多相关视频

Transcriptional Analysis by Nascent RNA FISH of In Vivo Trophoblast Giant Cells or In Vitro Short-term Cultures of Ectoplacental Cone Explants
08:26

Transcriptional Analysis by Nascent RNA FISH of In Vivo Trophoblast Giant Cells or In Vitro Short-term Cultures of Ectoplacental Cone Explants

Published on: August 31, 2016

8.4K
Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform
09:04

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

Published on: January 30, 2017

8.2K

相关实验视频

Last Updated: Mar 21, 2026

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation
12:09

Protocol for Human Blastoids Modeling Blastocyst Development and Implantation

Published on: August 10, 2022

7.6K
Transcriptional Analysis by Nascent RNA FISH of In Vivo Trophoblast Giant Cells or In Vitro Short-term Cultures of Ectoplacental Cone Explants
08:26

Transcriptional Analysis by Nascent RNA FISH of In Vivo Trophoblast Giant Cells or In Vitro Short-term Cultures of Ectoplacental Cone Explants

Published on: August 31, 2016

8.4K
Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform
09:04

Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform

Published on: January 30, 2017

8.2K

科学领域:

  • 发育生物学
  • 基因组学
  • 生殖医学

背景情况:

  • 人类的植入前发育对于成功怀孕至关重要.
  • 由于胚胎的可用性和动物模型的依赖,现有知识是有限的.
  • 了解特定物种的发展途径至关重要.

研究的目的:

  • 提供早期人类胚胎的全面转录组分析.
  • 确定人类植入前发展的独特特征.
  • 克服目前研究方法的局限性.

主要方法:

  • 大批人类植入前胚胎的单细胞RNA测序 (scRNA-seq).
  • 进行广泛的转录组分析.
  • 与现有的发育数据进行比较分析.

主要成果:

  • 在早期人类发育中识别以前未知的分子特征.
  • 在单细胞分辨率下详细的转录组概况.
  • 发现人类独特的新发育途径.

结论:

  • 这项研究为人类早期发展提供了前所未有的洞察力.
  • 这些发现突出了人类与其他哺乳动物胚胎发育之间的关键差异.
  • 这项资源将促进生殖生物学和发育障碍的研究.