自发性下关节出血
R Loch Macdonald1, Tom A Schweizer1
1Division of Neurosurgery, St Michael's Hospital, Toronto, ON, Canada; Labatt Family Centre of Excellence in Brain Injury and Trauma Research, St Michael's Hospital, Toronto, ON, Canada; Department of Surgery, University of Toronto, Toronto, ON, Canada.
Lancet (London, England)
|September 18, 2016
概括
脑下出血通常是由动脉瘤破裂引起的,是一种严重的中风. 虽然生存率有所提高,但幸存者经常面临认知障碍和情绪障碍,影响生活质量.
科学领域:
- 神经学
- 神经外科
- 脑卒中医学
背景情况:
- 副关节出血 (SAH) 是一种严重的中风亚型,通常由内动脉瘤破裂引起.
- SAH 影响个体平均年龄为 55 岁, 显著影响生产寿命.
研究的目的:
- 审查目前对神经瘤下关节出血的理解和治疗.
- 确定SAH研究和治疗的挑战和未来方向.
主要方法:
- 审查现有的临床试验和脑下出血的治疗策略.
- 对生存趋势,治疗结果和长期后果的分析.
主要成果:
- 由于改善的诊断,早期修复,尼莫迪平和重症监护,瘤下关节出血的存活率增加了17%.
- 幸存者经常会出现认知障碍,情绪障碍,疲劳和睡眠障碍,影响日常活动和生活质量.
- 只有两种干预措施在临床试验中显示出改善的结果.
结论:
- 专业的神经重症监护和高人数中心的多学科专业知识对于SAH管理至关重要.
- 未来的努力应集中在预防策略,改善查,减少侵袭性动脉瘤修复技术以及加强包括神经认知功能和生物标志物在内的结果评估上.
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