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相关概念视频

Pancreas01:19

Pancreas

2.5K
The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
2.5K
Cells and Secretions of the Pancreas01:16

Cells and Secretions of the Pancreas

5.4K
The pancreas, a vital organ within the abdominal cavity, plays dual roles in the digestive and endocrine systems, collaborating with exocrine and endocrine cells to maintain optimal digestion and blood sugar levels.
Exocrine function is carried out by acinar cells, organized into clusters known as acini. These cells contribute to digestion by releasing substantial quantities of enzyme-rich, alkaline digestive juices.
Concurrently, the dispersed clusters of endocrine cells throughout the...
5.4K
Whole Body Regeneration01:33

Whole Body Regeneration

4.2K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
4.2K
Liver Regeneration01:24

Liver Regeneration

4.4K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
4.4K
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

5.2K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
5.2K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.7K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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相关实验视频

Updated: Feb 10, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
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Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

Published on: July 27, 2022

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胰腺再生

Qiao Zhou1,2, Douglas A Melton3,4,5

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA. qiao_zhou@harvard.edu.

Nature
|May 18, 2018
PubMed
概括
此摘要是机器生成的。

恢复胰腺β细胞质量对于治疗1型糖尿病至关重要. 研究人员正在探索干细胞治疗和其他创新的胰腺再生策略.

更多相关视频

Isolation and Decellularization of a Whole Porcine Pancreas
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Isolation and Decellularization of a Whole Porcine Pancreas

Published on: October 10, 2018

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Collection Protocol for Human Pancreas
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Collection Protocol for Human Pancreas

Published on: May 23, 2012

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相关实验视频

Last Updated: Feb 10, 2026

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation
09:01

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

Published on: July 27, 2022

2.5K
Isolation and Decellularization of a Whole Porcine Pancreas
09:08

Isolation and Decellularization of a Whole Porcine Pancreas

Published on: October 10, 2018

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Collection Protocol for Human Pancreas
07:49

Collection Protocol for Human Pancreas

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科学领域:

  • 内分泌学
  • 复原医学
  • 细胞生物学

背景情况:

  • 胰腺具有外分泌和内分泌功能,分别产生消化酶和胰岛素.
  • 在1型糖尿病中产生胰岛素的β细胞损失需要治疗策略.
  • 人类小岛的再生能力有限.

研究的目的:

  • 审查目前恢复β细胞质量的治疗方法.
  • 突显胰腺再生中的各种策略的潜力.

主要方法:

  • 目前关于β细胞再生的研究.
  • 来自干细胞的β细胞生成和移植的分析.
  • 对内部细胞增殖和细胞重编程等替代方法的评估.

主要成果:

  • 人类多能干细胞为产生新的β细胞提供了一个有前途的来源.
  • 刺激内源性β细胞增殖和重新编程非β细胞是可行的替代策略.
  • 来自基因工程动物的小岛的异种移植也在调查中.

结论:

  • 目前正在开发多种治疗策略来进行胰腺再生.
  • 这些方法旨在恢复用于糖尿病治疗的β细胞质量和功能.