Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cell Adhesion in Plants01:14

Cell Adhesion in Plants

3.4K
Plants have rigid cell walls that are made up of cell wall polysaccharides that mediate cell-cell adhesion. The primary cell walls of plants consist of two independent and interacting polysaccharide networks: a pectin matrix that embeds the second network comprising cellulose and hemicelluloses.
Pectins are complex heteropolymers mainly composed of negatively-charged α-D-glucopyranosyl uronic acid and some neutral glycosyl residues such as α-L-rhamnopyranose, α-L-arabinofuranose,...
3.4K
Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

4.4K
Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
4.4K
Cell Adhesion Molecules - Types and Functions01:20

Cell Adhesion Molecules - Types and Functions

9.7K
Cell adhesion molecules (CAMs) are pivotal to multicellularity and the coordinated functioning of tissues and organ systems. They enable physical interactions between cells and provide mechanical strength to tissues. They also function as receptors for signal transmission across the plasma membrane. The CAMs are broadly classified into four families - integrins, cadherins, selectins, and immunoglobulin-like CAMs (IgCAMs).
CAM Families
The Integrin family of proteins is primarily  involved...
9.7K
Bacterial Signaling01:30

Bacterial Signaling

40.9K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
40.9K
Bacterial Cell Wall01:22

Bacterial Cell Wall

3.6K
The bacterial cell wall is an essential structural component that encases the plasma membrane, preserving cellular integrity, determining shape, and protecting against osmotic stress. This rigid yet flexible structure primarily comprises peptidoglycan, a polymer that forms a mesh-like matrix conferring mechanical strength and flexibility.Peptidoglycan Composition and StructurePeptidoglycan, the core of the bacterial cell wall, comprises alternating units of N-acetylglucosamine (NAG) and...
3.6K
Adhesion01:14

Adhesion

44.5K
Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
Capillary action is a result of water’s adhesive tendencies. When a narrow...
44.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Unifying regulatory motifs in endocrine circuits.

Nature communications·2025
Same author

Tuning viscoelasticity and fine structure of living materials via synthetic adhesion logic and rheological perturbations.

bioRxiv : the preprint server for biology·2025
Same author

Preventing Multimer Formation in Commonly Used Synthetic Biology Plasmids.

ACS synthetic biology·2025
Same author

Structure, motion, and multiscale search of traveling networks.

Nature communications·2025
Same author

Light-dependent switching between two flagellar beating states selects versatile phototaxis strategies in microswimmers.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Optogenetic patterning generates multi-strain biofilms with spatially distributed antibiotic resistance.

Nature communications·2024

相关实验视频

Updated: Feb 7, 2026

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer
09:37

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Published on: April 27, 2020

11.7K

合成细菌细胞粘附工具箱用于编程多细胞形态和模式

David S Glass1, Ingmar H Riedel-Kruse1

  • 1Department of Bioengineering, Stanford University, 318 Campus Drive, Stanford, CA 94305, USA.

Cell
|July 24, 2018
PubMed
概括

科学家们设计了一个合成平台来控制细菌细胞如何粘在一起. 这种遗传工具可以精确地组装多细胞结构,推进合成生物学和早期生命进化的研究.

科学领域:

  • 合成生物学
  • 微生物学
  • 生物物理

背景情况:

  • 合成的多细胞系统为研究自然发展和工程复杂的生物功能提供了强大的模型.
  • 目前控制细胞粘附的局限性阻碍了这些系统的精确组装.
  • 需要基因编码工具来指导细胞相互作用和多细胞组织.

研究的目的:

  • 开发一种100%基因编码的合成平台,用于大肠杆菌的模块细胞粘附.
  • 提供对多细胞自组和组织的精确控制.
  • 为了实现定义的多细胞形态和模式的合理设计.

主要方法:

  • 使用外膜显示纳米体和抗原的图书馆进行选择性细胞粘附.
  • 粘附系统中的工程直角特征.
  • 通过内在粘附特性,竞争性抑制和诱导性表达来控制粘附亲和力.

主要成果:

  • 经过精确定义的形态和模式的量化合理设计.
  • 通过同型和异型相互作用实现多细胞自我组合的控制.
  • 展示了类似格子组装,相分离,差异粘附和顺序分层的能力.

结论:

关键词:
粘附性形态学多细胞性纳米体图案设计自动组装自主组织合成生物学

更多相关视频

In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells
05:57

In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells

Published on: May 16, 2011

26.6K
Introducing Shear Stress in the Study of Bacterial Adhesion
13:28

Introducing Shear Stress in the Study of Bacterial Adhesion

Published on: September 2, 2011

16.3K

相关实验视频

Last Updated: Feb 7, 2026

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer
09:37

Preparing Protein Producing Synthetic Cells using Cell Free Bacterial Extracts, Liposomes and Emulsion Transfer

Published on: April 27, 2020

11.7K
In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells
05:57

In Vitro Assay of Bacterial Adhesion onto Mammalian Epithelial Cells

Published on: May 16, 2011

26.6K
Introducing Shear Stress in the Study of Bacterial Adhesion
13:28

Introducing Shear Stress in the Study of Bacterial Adhesion

Published on: September 2, 2011

16.3K
  • 开发的合成粘附平台提供了对大肠杆菌多细胞性的模块化控制.
  • 这种工具箱可以构建高水平的多细胞设计和复杂的生物材料.
  • 该系统提供了从单细胞到多细胞生命的进化过渡的见解.