作者纠正:胚胎干细胞分化过程中LSD1的增强器退役
Warren A Whyte1,2, Steve Bilodeau1, David A Orlando1
1Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.
Nature
|September 14, 2018
概括
该字母对LSD1和素的西部抹黑数据进行了校正,确保了蛋白质水平的准确表示. 修正案澄清了车道并置问题,并提供了科学发现透明度的原始数据.
科学领域:
- 分子生物学
- 生物化学
背景情况:
- 西方涂抹是蛋白质分析的一个关键技术.
- 准确的数据呈现对于科学完整性至关重要.
研究的目的:
- 为了纠正西方数字中的无意错误.
- 确保LSD1,蛋白和HDAC1蛋白水平的准确表示.
- 为了透明度提供更正的数字和原始数据.
主要方法:
- 西方涂抹用于分析蛋白质表达.
- 进行图像分析和图像编制.
- 修改包括纠正重复图像和划分非相邻的车道.
主要成果:
- 发现并纠正了LSD1的突斑的意外重复.
- 提供了对LSD1,图布林和HDAC1进行校正的西部斑点.
- 图中添加了垂直线,以澄清车道的并置.
结论:
- 校正确保了蛋白质表达数据的准确描述.
- 修订后的数字和补充数据增强了研究结果的可靠性.
- 通过提供原始图像来保持数据呈现的透明度.
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