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相关概念视频

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
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Myasthenia Gravis: Diagnostic Tests01:15

Myasthenia Gravis: Diagnostic Tests

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Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
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Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

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Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
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Chemical Synapses01:26

Chemical Synapses

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Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
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Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

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The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
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Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
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Author Spotlight: Translational Applications of Stimulated SFEMG in Rodent Models
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与COVID-19相关的神经肌肉疾病

Larry Morgan1, Mary Hollist2, Katherine Au3

  • 1Bronson Neuroscience Center, Kalamazoo, MI, USA.

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冠状病毒疾病2019 (COVID-19) 流行病影响神经肌肉疾病,导致呼吸系统问题以外的各种病理. 这篇评论探讨了COVID-19的情况.

关键词:
在 COVID-19 疫情中,肌痛性骨髓灰质炎 (Myasthenia Gravis) 是一个严重的疾病.神经肌肉的神经肌肉神经病变是一种神经病变.麻性 麻性 麻性

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科学领域:

  • 神经学 神经学
  • 传染性疾病 传染性疾病
  • 关键护理医学 关键护理医学

背景情况:

  • COVID-19大流行严重影响了先前存在神经肌肉疾病的个体.
  • SARS-CoV-2 感染呈现出广泛的神经肌肉并发症,超越呼吸系统症状.
  • 了解这些神经系统序列对于患者的管理和预后至关重要.

研究的目的:

  • 审查COVID-19感染与神经肌肉系统之间的多方面的关系.
  • 列出和讨论与SARS-CoV-2相关的各种神经肌肉并发症.
  • 突出COVID-19对先前存在的神经肌肉疾病的患者的影响.

主要方法:

  • 文献综述综合了有关COVID-19和神经肌肉疾病的当前知识.
  • 对已记录的病例和临床观察的分析.
  • 讨论将SARS-CoV-2与神经肌肉系统功能障碍联系在一起的病理机制.

主要成果:

  • COVID-19与直接和间接的神经肌肉并发症有关.
  • 报告的疾病包括严重疾病神经肌病,外围神经,肌痛和位置性压缩性神经病变.
  • 观察到已经存在的疾病的恶化,如肌痛性肌痛症和吉兰-巴雷综合征.

结论:

  • COVID-19对感染者和以前患有神经肌肉疾病的人来说,对神经肌肉系统构成重大风险.
  • 对这些多样化的神经系统表现的全面理解和认知是必不可少的.
  • 需要进一步的研究来阐明长期的神经肌肉结果和优化治疗策略.