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相关概念视频

Cell Specific Gene Expression01:58

Cell Specific Gene Expression

13.6K
Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
13.6K

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相关实验视频

Updated: Jul 27, 2025

Using Fluorescence Activated Cell Sorting to Examine Cell-Type-Specific Gene Expression in Rat Brain Tissue
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Using Fluorescence Activated Cell Sorting to Examine Cell-Type-Specific Gene Expression in Rat Brain Tissue

Published on: May 28, 2015

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特定于细胞类型的细胞类型.

Ban Wang1, Alexander L Starr1, Hunter B Fraser1

  • 1Department of Biology, Stanford University, Stanford, CA, USA.

bioRxiv : the preprint server for biology
|June 9, 2023
PubMed
概括
此摘要是机器生成的。

细胞类型特定的基因调节推动了人类进化. 研究人员分析了六种细胞类型的基因表达和染色质可访问性,以确定人类特异性的调节变化,揭示了专门基因的更快进化.

科学领域:

  • 进化生物学是进化的生物学.
  • 基因组学就是基因组学.

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Cell Type-specific Gene Expression Profiling in the Mouse Liver
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Single-cell RNA-Seq of Defined Subsets of Retinal Ganglion Cells
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相关实验视频

Last Updated: Jul 27, 2025

Using Fluorescence Activated Cell Sorting to Examine Cell-Type-Specific Gene Expression in Rat Brain Tissue
08:37

Using Fluorescence Activated Cell Sorting to Examine Cell-Type-Specific Gene Expression in Rat Brain Tissue

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Cell Type-specific Gene Expression Profiling in the Mouse Liver
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Cell Type-specific Gene Expression Profiling in the Mouse Liver

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Single-cell RNA-Seq of Defined Subsets of Retinal Ganglion Cells
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Single-cell RNA-Seq of Defined Subsets of Retinal Ganglion Cells

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  • 细胞生物学 细胞生物学

    • 背景情况:

    • 基因表达分歧被认为是人类进化的关键驱动力.
    • 鉴定人类特征的特定基因和变异是具有挑战性的.
    • 特定于细胞类型的 cis-regulatory 变体提供了一个精确的进化适应机制.

    结论:

    • 跨细胞类型的 cis-regulatory 分歧的综合性分析对于识别人类特异性遗传变化至关重要.
    • 细胞类型特定的调控变化在人类进化中起着重要作用.
    • 这种方法可以揭示人类独特特征背后的遗传变异.