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相关概念视频

Anatomy of the Ear01:16

Anatomy of the Ear

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Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Assessing Body Temperature - Tympanic membrane01:14

Assessing Body Temperature - Tympanic membrane

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Assessing tympanic membrane temperature involves using a tympanic membrane thermometer (TMT). Here is a step-by-step guide:
Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
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Computed Tomography01:10

Computed Tomography

4.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.6K
The Auditory Ossicles01:11

The Auditory Ossicles

1.7K
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
1.7K

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相关实验视频

Updated: Jul 25, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

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用光学连贯性断层扫描评估中耳结构和功能.

Sebastiaan W F Meenderink1, Michael Warn2, Laura M Anchondo1

  • 1VA Loma Linda Healthcare System, Loma Linda, CA, USA.

Acta oto-laryngologica
|June 27, 2023
PubMed
概括

光谱域光学一致性断层扫描 (SD-OCT) 无创地可视化中耳的解剖学和功能. 这项技术可以评估耳膜和骨振动,帮助导电性听力损失诊断.

关键词:
光学连贯性断层扫描仪传导性听力损失是指传导性听力损失.中耳的中间耳朵.中耳的声音传输传输.骨头的骨头是一个骨头.tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic tympanic

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Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
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Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats
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科学领域:

  • 生物医学工程 生物医学工程
  • 耳鼻喉科 耳鼻喉科 耳鼻喉科
  • 医疗成像医学成像

背景情况:

  • 目前中耳损伤和导电性听力损失 (CHL) 的临床试验耗时且昂贵.
  • 现有的方法缺乏对ME结构和功能的非侵入性实时评估.
  • 光学连贯断层扫描 (OCT) 提供结构和功能评估,但在听力学中未得到充分利用.

研究的目的:

  • 适应商业光谱域OCT (SD-OCT) 系统用于评估人类ME解剖学.
  • 使用SD-OCT测量耳膜 (TM) 和骨的声音引起的振动.
  • 评估SD-OCT在诊断导致CHL的ME疾病方面的潜力.

主要方法:

  • 在新鲜的人类骨上使用商业SD-OCT系统.
  • 捕获了中耳的高分辨率3D图像.
  • 采用相位感应振动计,与软件适应,以测量TM和骨的声音诱导的振动.

主要成果:

  • 生成了耳膜的3D厚度图.
  • 观察到多种模式的TM振动,复杂度随频率增加.
  • 通过TM传输到骨的测量振动,量化声音传输.
  • 成功量化了中耳声传输,这是CHL评估的关键指标.

结论:

  • 适应的SD-OCT成功地可视化了人类的ME解剖学和功能.
  • SD-OCT证明了革命性地改变ME病理的临床评估的潜力.
  • 这项技术可以识别导致CHL的ME干扰,而这些干扰往往被耳视镜遗漏.