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Updated: Jul 23, 2025

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
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Published on: May 10, 2018

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由uORFs进行翻译性调节和启动密码区选择严格性

Thomas E Dever1, Ivaylo P Ivanov1, Alan G Hinnebusch1

  • 1Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA thomas.dever@nih.gov ivaylo.ivanov@nih.gov ahinnebusch@nih.gov.

Genes & development
|July 11, 2023
PubMed
概括

上游开放阅读框架 (uORF) 通过控制主开放阅读框架 (mORF) 的翻译来调节基因表达. 本综述探讨了uORFs如何抑制或刺激翻译,重点关注核糖体队列和延迟重新启动模型的替代方案.

关键词:
在ATF4中使用ATF4.在 GCN4 中.通过eIF2酸化.核糖体排队排队是什么意思这是一个严格的严格性.在 uORF 的情况下.

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