患有多发性硬化症的成年人的并发性疾病和身体功能
Brenda Jeng1, Trinh L T Huynh2, Robert W Motl1
1Department of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL; Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL.
更多的并发症,特别是高血压和骨关节炎,与多发性硬化症 (MS) 患者的身体功能恶化有关. 针对这些情况的干预措施可以改善流动性.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 公共卫生 公共卫生
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经疾病,影响身体功能.
- 伴随性疾病在MS中很常见,可能会影响疾病的进展和患者的结果.
- 了解并发症和身体功能之间的关系对于有效的管理至关重要.
研究的目的:
- 调查与多发性硬化症患者共患病的总数与身体功能之间的关联.
- 确定MS中特定的常见并发症及其对身体功能结果的影响.
- 探索旨在改善MS体育功能的干预措施的潜在目标.
主要方法:
- 在大学实验室环境中进行了一项横截面的比较研究.
- 二百七名患有多发性硬化症的参与者 (N=207) 提供了人口统计,临床和并发性疾病数据.
- 使用6分钟步行 (6MW),定时25英尺步行 (T25FW),定时Up and Go (TUG) 和短物理性能电池 (SPPB) 来评估身体功能.
主要成果:
- 更多的并发性疾病与所有身体功能指标 (6MW,T25FW,TUG,SPPB;P≤.001) 的较差得分显著相关.
- 与没有高血压的人相比,患有多发性硬化和高血压的人在所有身体功能测试中表现较差.
- 与没有骨关节炎的人相比,患有骨关节炎的参与者在6MW,T25FW和SPPB中也表现出身体功能下降.
结论:
- 增加的并发症负担与MS患者的身体功能下降相关.
- 高血压和骨关节炎似乎是这群人体身体功能缺陷的重要贡献者.
- 侧重于身体活动和饮食的行为干预,针对并发性疾病,有望提高MS患者的身体功能.
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