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在轨道细胞炎中微生物模式和培养实用性
Yvette Schein1, Lisa Y Lin2, Karen Revere3
1Division of Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.
概括
非手术培养不适用于儿童的轨道细胞炎的管理,因为他们很少改变治疗或避免手术. 链球菌和对甲素敏感的金黄色葡萄球菌 (MSSA) 是已识别的最常见的病原体.
科学领域:
- 眼科医生 眼科 眼科
- 儿童传染病 儿童传染病
- 微生物学 微生物学
背景情况:
- 轨道细胞炎是一种严重的感染,需要及时诊断和治疗.
- 鉴定致病原体对于有效治疗至关重要,但非手术培养的有用性仍在争论中.
研究的目的:
- 确定儿科轨道细胞炎中病原体的流行率和类型.
- 评估非手术培养在指导管理和避免手术的有效性.
主要方法:
- 在8年内对有成像证实轨道细胞炎的儿童进行了回顾性队列研究.
- 对病原体患病率的分析,包括多微生物和无氧感染.
- 评估与手术干预和治疗变化有关的培养效用.
主要成果:
- 在220名儿童中,112名儿童接受了培养;69名儿童接受了手术.
- 常见的病原体包括Streptococcus anginosus群 (17%),对甲素敏感的金黄色葡萄球菌 (MSSA) (13%),以及Streptococcus pyogenes (11%).
- 在98%的病例中,非手术培养没有帮助,无法改变管理或避免手术.
结论:
- 链球菌和MSSA是儿科轨道细胞炎中最常见的病原体.
- 甲素耐药黄金葡萄球菌 (MRSA) 不常见,可能不需要初步的经验覆盖.
- 非手术培养不适用于轨道细胞炎的初始治疗,因为它们具有有限的临床效用.
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