Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Birth Control Methods01:22

Birth Control Methods

337
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
337
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

444
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
444
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

576
The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle.  At puberty, GnRH secretion increases in both frequency and...
576
Hormonal Regulation01:33

Hormonal Regulation

33.3K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
33.3K
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

3.5K
Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral...
3.5K
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

1.5K
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
1.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Intravenous and Subcutaneous Pharmacokinetic Modeling to Support the Development of Long-Acting Multipurpose Prevention Technology for HIV and Pregnancy.

Biomedicines·2026
Same author

First-in-line 3D-printed intravaginal ring for nonhormonal contraception.

Drug delivery and translational research·2026
Same author

First-in-line 3D-printed intravaginal ring for nonhormonal contraception.

Research square·2025
Same author

Next Generation 3D Printed Multipurpose Intravaginal Ring For Sustained Co-Delivery of Antiretroviral Drugs and A Contraceptive Hormone.

Pharmaceutical research·2025
Same author

First-in-line subcutaneous injectable for reversible, non-hormonal male contraception.

Drug delivery and translational research·2025
Same author

Injectable Tumoricidal Neural Stem Cell-Laden Hydrogel for Treatment of Glioblastoma Multiforme-An In Vivo Safety, Persistence, and Efficacy Study.

Pharmaceutics·2025
Same journal

Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.

Journal of clinical medicine·2026
Same journal

Surgical and Transcatheter Approach of a Failed Mitral Valve Repair: A Comprehensive Review on Selecting the Most Suitable Approach.

Journal of clinical medicine·2026
Same journal

Hybrid Metaheuristic Feature Selection for Breast Cancer Detection in Digital Mammography: A Feasibility Study with Nested Validation, Benchmarking, and External Stress Testing.

Journal of clinical medicine·2026
Same journal

Identity Transformation and the Role of Accountability in Recovery from Problematic Pornography Use: A Phenomenological-Hermeneutical Study.

Journal of clinical medicine·2026
Same journal

Does Early Surgical Treatment in Degenerative Cervical Myelopathy Have a Favorable Clinical Outcome and Impact on Quality of Life?

Journal of clinical medicine·2026
Same journal

Shear Wave Elastography in Musculoskeletal Imaging: A Narrative Review.

Journal of clinical medicine·2026
查看所有相关文章

相关实验视频

Updated: Jul 21, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

6.0K

非荷尔蒙避孕药是一种非荷尔蒙避孕药.

Sarah Anne Howard1, Soumya Rahima Benhabbour1,2

  • 1Division of Pharmacoengineering and Molecular Pharmaceutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Journal of clinical medicine
|July 29, 2023
PubMed
概括
此摘要是机器生成的。

开发新的非荷尔蒙避孕药非常重要,因为荷尔蒙选择面临安全问题,现有的非荷尔蒙方法有局限性. 本综述探讨了有效,可逆妊娠预防的新目标和候选药物.

关键词:
作为一种避孕手段.长时间起作用的药物.其他非荷尔蒙性作用.这是一种可逆的可逆性.

更多相关视频

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
04:37

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians

Published on: May 12, 2019

15.7K
Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
09:05

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle

Published on: August 30, 2021

7.5K

相关实验视频

Last Updated: Jul 21, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
08:46

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives

Published on: September 16, 2021

6.0K
Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
04:37

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians

Published on: May 12, 2019

15.7K
Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
09:05

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle

Published on: August 30, 2021

7.5K

科学领域:

  • 生殖生物学和药理学生殖生物学和药理学
  • 避孕药的发展与开发

背景情况:

  • 荷尔蒙避孕药是有效的,但引发了安全问题,阻止了许多使用者.
  • 目前的非荷尔蒙避孕药包括绝育,铜IUD,屏障和传统方法,对于未来的生育能力保护而言,可逆选择有限.
  • 高比例的意外怀孕需要开发新的避孕策略.

研究的目的:

  • 审查已识别的非荷尔蒙避孕点.
  • 讨论目前正在开发的非荷尔蒙避孕药物候选药物.
  • 探索女性和男性预防怀孕的创新方法.

主要方法:

  • 现有和新兴的非激素避孕药研究的文献综述.
  • 针对新型避孕药的关键生殖过程的分析.
  • 基于这些目标,识别候选药物.

主要成果:

  • 已经确定了几种非激素避孕药在关键生殖过程中的点.
  • 各种候选药物正在开发中,为新的可逆避孕选择提供了潜在的潜力.
  • 该审查强调了这些新方法的科学基础.

结论:

  • 针对关键生殖途径的新型非荷尔蒙避孕药正在开发中.
  • 这些进展有望改善避孕选择,解决未满足的需求,减少意外怀孕.
  • 进一步的研究和临床试验至关重要,以使这些候选者取得成果.