DLPFC-PPC-cTBS对元认知意识的影响
Antonio Martin1, Timothy J Lane2, Tzu-Yu Hsu2
1Graduate Institute of Mind, Brain and Consciousness (GIMBC), Taipei Medical University, Taipei, Taiwan.
概括
连续的甲爆跨磁刺激 (cTBS) 在背侧前额叶皮层上,但不是皮层,减少了虚幻人物的元认知效率. 对于真实数字的发现是不确定的,这表明进一步调查大脑中介于元认知的区域.
科学领域:
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
- 大脑刺激 大脑刺激
背景情况:
- 神经成像和病变研究表明,视觉元认知中涉及背侧前额叶和后额叶皮层.
- 之前关于这些区域在元认知中的因果作用的非侵入性脑刺激研究已经产生了不一致的结果.
研究的目的:
- 调查双边背侧前额外皮和后额外皮在感知元认知中的因果作用,使用连续的甲爆跨磁刺激 (cTBS).
- 确定这些地区的cTBS是否会影响真实和虚幻数字任务中的主观可见度评分和元认知效率.
主要方法:
- 一个在主体内设计的三个会议,每一个应用双边cTBS到前额,额叶或控制皮层.
- 参与者同时执行了真实和虚幻数字歧视任务,使用自适应式楼梯程序稳定了客观性能.
- 在cTBS之后评估了元认知效率和可见度等级.
主要成果:
- 在背侧前额叶皮层的cTBS,但不是后额叶皮层,显著降低了Kanizsa虚幻人物的元认知效率.
- 在任何一个地区,在cTBS之后的真实数字任务中,没有观察到可见度评级或元认知效率的显著扰乱.
- 这些差异效应表明,这些皮质区域在处理真实与虚幻刺激方面有着不同的作用.
结论:
- 背侧前额叶皮层似乎在元认知效率中起着因果作用,特别是对于虚幻刺激,可能是通过期望生成.
- 后壁皮质在元认知中的作用仍然不太清楚,在任务之间有不一致的发现.
- 该研究强调了cTBS的任务依赖性影响以及需要进一步的研究,以确定这些大脑区域对元认知意识的因果贡献.
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