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Updated: Jul 20, 2025

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设计一种CEACAM1变体,对TIM-3受体具有增加的结合亲和力

Zahra Hajihassan1, Mehran Mohammadpour Saray1, Aysan Yaseri1

  • 1Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran.

Iranian biomedical journal
|August 1, 2023
PubMed
概括

研究人员设计了CEACAM1的一个变体 (变体39) 来阻止T细胞免疫球蛋白和粘素域-3 (TIM-3). 这种变体对TIM-3具有明显更高的结合亲和力,为免疫相关疾病提供了有前途的治疗策略.

关键词:
结合性亲缘关系是一种结合性亲缘关系.突变发生是突变发生的.这是一种TIM-3蛋白质.

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