在巴罗受体加载和卸载过程中出现快速开始的血管扩张
Olivia K Leach1, Jayson R Gifford1, Gary W Mack1
1Department of Exercise Sciences, Brigham Young University, Provo, Utah, United States.
概括
肌肉收缩后的快速发作的血管扩张 (ROV) 受巴罗受体压力变化的影响. 在对血管反应的研究中,为准确的ROV比较,调整峰值肌肉力量至关重要.
科学领域:
- 心血管生理学心血管生理学
- 运动生理学 运动生理学
- 自主神经系统的自主神经系统
背景情况:
- 肌肉收缩引起迅速发作的血管扩张 (ROV),这是一个关键的血管反应.
- 巴罗受体的加载和卸载可以调节自主神经系统的活动.
- 肌肉收缩诱导的血管扩张和巴罗受体反射之间的相互作用尚未完全理解.
研究的目的:
- 调查巴罗受体的加载和卸载是否会改变肌肉收缩后血管导电率的增加.
- 为了确定峰值肌肉力量和ROV之间的关系.
- 测试气体感应器压力变化是否对ROV产生比例影响.
主要方法:
- 参与者在最大自愿收缩的50%时经历了单个肌肉收缩.
- 测量了手臂动脉的血流量 (多普勒超声波) 和平均动脉压 (Finapress).
- 计算了血管导电量,并使用下体正负压 (LBPP/LBNP) 来量化ROV来操纵巴罗受体输入.
主要成果:
- 发现ROV与肌肉收缩的峰值力线性成比例.
- 与对照组相比,在巴罗受体卸载过程中ROV显著降低 (例如,-40 mmHg LBNP).
- 随着气体受体负荷的增加 (例如,+20 mmHg LBPP),ROV增加,并在测试范围中与室内压力呈现线性关系.
结论:
- 由巴罗受体操纵诱导的血管收缩体调的生理相关变化,比例地改变ROV.
- 在对个人或条件的ROV进行比较时,必须将峰值肌肉力量视为共变量.
- 准确评估ROV需要考虑肌肉收缩强度和巴罗受体状态.
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