Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

381
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
381
Human Genetics01:28

Human Genetics

588
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
588
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

45
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
45
Typical Model Studies01:30

Typical Model Studies

365
Fluid mechanics model studies often utilize scaled-down systems to predict fluid behavior in full-scale environments, such as river flows, dam spillways, and structures interacting with open surfaces. Maintaining Froude number similarity in river models is crucial, as it replicates surface flow features like wave patterns and velocities.
365
Longitudinal Studies01:26

Longitudinal Studies

171
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
171
The Ratio of X Chromosome to Autosomes02:45

The Ratio of X Chromosome to Autosomes

8.6K
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.  
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
8.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multivariate genetic analyses of 2.2 million individuals reveal broad and substance-specific pathways of addiction risk.

Nature. Mental health·2026
Same author

Genomic insights into substance use and disinhibitory disorders.

medRxiv : the preprint server for health sciences·2026
Same author

Substance use disorders exhibit unique and disorder specific genetic associations with externalizing and internalizing psychopathology.

medRxiv : the preprint server for health sciences·2026
Same author

Mapping the genetic landscape across 14 psychiatric disorders.

Nature·2025
Same author

The power of parenting: mitigating conduct problems among adolescents carrying genetic risk.

Frontiers in child and adolescent psychiatry·2025
Same author

The broad structure of psychopathology in the All of Us Research Program.

Psychological medicine·2025

相关实验视频

Updated: Jul 13, 2025

Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills
06:52

Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills

Published on: September 17, 2019

6.4K

通过使用定量遗传分析评估青年外部化的替代模型.

Irwin D Waldman1, Holly E Poore2

  • 1Emory University, Department of Psychology.

Journal of psychopathology and clinical science
|October 16, 2023
PubMed
概括

更详细的模型更好地解释了年轻人的外部化行为. 双胞胎数据的定量遗传分析表明,外化症状的细粒度模型比更广泛的模型提供了更平衡的遗传和环境影响的观点.

科学领域:

  • 发展心理学 发展心理学
  • 行为遗传学 行为遗传学
  • 心理病理学研究 心理病理学研究

背景情况:

  • 层次模型越来越多地被用来描述心理病理的尺寸.
  • 心理病理学的外部化维度在成年人中得到了很好的研究,但在年轻人中却不那么多.
  • 划分青年外化频谱需要精细的结构和遗传分析.

研究的目的:

  • 为了比较年轻人外部化行为的替代定量遗传模型.
  • 评估遗传和环境对外部化维度和特定症状的影响.
  • 确定青少年心理病理外化模型的最佳细分度.

主要方法:

  • 对883对年轻双胞胎 (年龄8.5岁) 的双胞胎数据进行了定量遗传分析.
  • 对38种外部化症状的母报告数据的分析.
  • 模型适合性和遗传/环境影响估计在不同模型细分度的比较.

主要成果:

  • 结合外部化和细粒度症状维度的潜在维度的模型显示出更好的匹配.
  • 这些颗粒模型表明,遗传和环境影响的分布更为平衡.
  • 广泛复合模型和潜变量模型之间的遗传性估计是可比的.

更多相关视频

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.0K
Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

1.7K

相关实验视频

Last Updated: Jul 13, 2025

Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills
06:52

Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills

Published on: September 17, 2019

6.4K
Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.0K
Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

1.7K

结论:

  • 更细致的青年外化行为模型提供了更细致的了解潜在的遗传和环境因素.
  • 这些详细的模型可以促进对特定外部化症状组件的原因和结果的研究.
  • 需要进一步复制以确认这些细粒度模型的实用性.