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Updated: Jul 12, 2025

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
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瘤抗原主导的树突细胞衍生外体与殖民地刺激因子-1受体抑制剂协同作用,通过调节瘤微环境和系统免疫力

Anjali Barnwal1,2, Vidit Gaur1,2, Anindita Sengupta1,2

  • 1Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi 110016, India.

ACS biomaterials science & engineering
|October 23, 2023
PubMed
概括

成熟的树突细胞衍生外体 (mDexTA) 与CSF-1R抑制剂 (PLX-3397) 结合,通过增强T细胞透和调节瘤微环境,有效延缓瘤生长并改善黑色素瘤模型的存活率.

关键词:
这是一种CSF-1R抑制剂.癌症免疫疗法癌症免疫疗法由直流衍生出来的异构体.黑色素瘤是一种黑色素瘤.在PLX-3397中使用.瘤微环境是一个微环境.

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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes11:48

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