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相关概念视频

Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
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基于水凝的微针作为药物输送系统

David Filho1,2, Marcelo Guerrero1,2, Manuel Pariguana1,2

  • 1Laboratory of Bio & Nano Materials, Drug Delivery and Controlled Release, Department of Microbiology, Faculty of Health Sciences, University of Talca, Talca 3460000, Chile.

Pharmaceutics
|October 28, 2023
PubMed
概括

水凝和微针结合起来,形成了先进的透皮药物递送系统 (TDDS). 这种创新方法提供了可控的局部药物释放,增强治疗结果和治疗可能性.

关键词:
生物医学应用程序系统交付系统的交付系统.这种水凝是水凝.微针是一种微针.

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科学领域:

  • 生物医学工程 生物医学工程
  • 材料科学 材料科学 材料科学
  • 药理学 药理学是指药理学的学科.

背景情况:

  • 皮肤作为最大的器官,提供了通过皮肤递送药物系统 (TDDS) 进行非侵入性药物管理的可访问途径.
  • 水凝 (HG) 和微针 (MNs) 是先进药物输送技术的关键组成部分.

研究的目的:

  • 探索混合水凝和微针 (HG-MN) 的应用,以提高药物输送效率.
  • 详细介绍HG-MN系统在通过皮肤给药时提供的优势.

主要方法:

  • 研究水凝矩阵的特性及其与微针技术的相互作用.
  • 分析用于药物输送应用的HG-MN系统的特性.

主要成果:

  • HG-MN表现出有利的特性,包括对外部刺激的反应能力,源自它们的水凝成分.
  • 这些系统可以控制,持续和局部释放药物.
  • 这种组合允许配方成分和多种生物活性剂之间的协同相互作用.

结论:

  • 基于HG-MN的系统在生物医学领域具有显著的优势.
  • 这项技术为改善药物的药理动力学和药理动力学提供了一个新的安全平台.
  • HG-MNs为药物治疗策略开辟了新的视角.