急性病患者使用类固醇:不断变化的建议和实践
1Program Director, Critical Care Medicine; Vice-Chair of Education, Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center; Professor of Medicine in Anesthesiology and Medicine, Weill Cornell Medical College, New York, NY; researcher and member of guidelines committees on the use of corticosteroids in acutely ill patients pastores@mskcc.org.
关键疾病相关的皮质类固醇缺乏症 (CIRCI) 涉及炎症和HPA轴调节失调. 本综述涵盖了目前对CIRCI诊断和关键疾病治疗的理解.
科学领域:
- 内分泌学 在内分泌学.
- 关键护理医学 关键护理医学
- 病理生理学 病理生理学
背景情况:
- 关键疾病相关的皮质类固醇缺乏症 (CIRCI) 具有全身炎症的特征.
- 它涉及下丘脑-垂体-上腺 (HPA) 轴的失调.
- 改变皮质醇代谢和组织对皮质类固醇的抵抗是关键特征.
研究的目的:
- 审查目前对CIRCI的理解和不断变化的建议.
- 提供诊断和治疗实践的概述.
主要方法:
- 关于CIRCI的当前思想的文献综述.
- 综合新出现的关于诊断和治疗的信息.
主要成果:
- CIRCI与诸如败血症,败血性休克,ARDS和严重肺炎等疾病有关.
- 对CIRCI的诊断和治疗策略正在不断发展.
结论:
- 了解CIRCI对于管理重症患者至关重要.
- 审查强调了CIRCI管理的动态性质.
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