糖尿病前期的进展和回归对客观测量的身体功能:一个前性队列研究
Shanhu Qiu1,2, Yiming Zhu3, Bo Xie1,2
1Department of General Practice, Institute of Diabetes, Zhongda Hospital, School of Medicine, Southeast University, Nanjing.
在老年人中,糖尿病前期的进展会使握力恶化. 在这项研究中,恢复正常血糖水平并没有防止与年龄相关的身体功能下降.
科学领域:
- 老年学是一门学科.
- 代谢健康 代谢健康
- 身体功能 身体功能
背景情况:
- 前糖尿病与老年人身体功能下降有关.
- 糖尿病前期进展或回归对身体功能的具体影响尚不清楚.
- 这项研究调查了糖尿病前期状态变化与身体功能之间的纵向关联.
研究的目的:
- 评估50岁以上美国成年人糖尿病前期进展/回归和身体功能之间的纵向关联.
- 为了确定糖尿病前期状态的变化是否会影响握力,步行速度和站立平衡.
- 提供关于在患有糖尿病前期的老年人群中管理身体功能的见解.
主要方法:
- 从健康和退休研究中对1511名50岁以上糖尿病前期的美国成年人进行了长度研究.
- 在4年内评估糖尿病前期状态的变化 (维持,回归,进展).
- 通过客观测量和回归分析,在另外4年内测量身体功能 (握力,步行速度,站立平衡).
主要成果:
- 糖尿病前期的进展与89%的发展弱握力和更大的握力下降的几率增加有关.
- 在糖尿病前期进展和步行速度或站立平衡受损之间没有发现显著的关联.
- 糖尿病前期的回归到正常血糖没有显著影响任何测量的身体功能结果.
结论:
- 糖尿病前期的进展加快了人口老龄化中的握力下降.
- 回归到正常血糖症可能无法完全缓解与年龄相关的身体功能下降.
- 维持糖尿病前期状态或回归到正常血糖并没有防止随着时间的推移,握力和步行速度的下降.
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