传染病对于鼻科医生来说是传染病
Lu Hui Png1,2, Dorothy Hui Lin Ng3, Neville Wei Yang Teo1
1Department of Otorhinolaryngology - Head and Neck Surgery, Singapore General Hospital, Singapore.
Current opinion in otolaryngology & head and neck surgery
|November 24, 2023
概括
最近的文献强调了COVID-19相关的嗅觉功能障碍 (OD) 和其变体依赖. 研究还探讨了慢性鼻炎 (CRS) 中的真菌感染和鼻腔微生物组.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 鼻感染涉及病毒,真菌和细菌病原体之间的复杂相互作用.
- 最近的进展揭示了COVID-19的后果以及鼻子微生物组在慢性鼻炎 (CRS) 中的作用.
研究的目的:
- 审查最近 (18个月) 关于鼻道病毒,真菌和细菌感染的文献.
- 总结COVID-19相关的嗅觉功能障碍 (OD) 和CRS中的鼻腔微生物组的发现.
主要方法:
- 在过去18个月内发表的研究的文献综述.
- 分析与COVID-19,真菌鼻炎和鼻腔微生物组合相关的发现.
主要成果:
- 与COVID-19相关的OD是变体依赖的,成像显示嗅觉裂变暗和嗅觉球泡变化.
- 嗅觉训练是主要的治疗方法,有新兴的疗法,如PRP注射和口服补充剂.
- 关于真菌鼻炎的共识声明已经发布.
- 葡萄球菌和Corynebacterium是主要的鼻腔属,在CRS患者和健康个体中丰富度不同,尽管关于CRS中微生物群生物多样性意义的证据是矛盾的.
结论:
- 由于COVID-19的后果,特别是OD,存在持续的治疗挑战.
- 对OD机制和治疗的进一步研究对于COVID-19后患者和潜在的其他人至关重要.
- 需要对鼻子微生物组在CRS发展和治疗中的作用进行更多的研究.
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