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Updated: Jul 9, 2025

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
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在Ig和非Ig位点的体质突变模式.

Edward J Steele1, Andrew Franklin2, Robyn A Lindley3

  • 1Melville Analytics Pty Ltd, 2/102 Duke St, Kangaroo Point, Brisbane 4169, Qld, Australia.

DNA repair
|December 6, 2023
PubMed
概括

反转录酶 (RT) 模型对免疫球蛋白 (Ig) 体质突变 (SHM) 进行了修订. DNA聚合酶eta和theta充当RTs,可能解释Ig和非Ig位点的突变特征,这些突变特征被PCR技术所掩盖.

关键词:
DNA 聚合酶-乙太.的DNA聚合酶-甲基.免疫球蛋白 (Ig) 基因在PCR重组人工制造物中.逆转录酶的使用方法身体上的超变异性突变.链偏差突变的突变这就是TP53的特点.

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