.

Karina Sanabria Ortiz1,2, José R Hernández Espinell1,2, Desire Ortiz Torres1,2

  • 1Department of Chemistry, University of Puerto Rico, Río Piedras Campus, San Juan, Puerto Rico 00931, United States.

Crystal growth & design
|December 18, 2023
PubMed
概括

制备方法显著影响固体分散的多态形式. 融合方法产生混合多态,而基于溶剂的方法产生单晶形式,这对于准确的相位图和药物质量至关重要.

相关概念视频

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Factors Affecting Dissolution: Polymorphism, Amorphism and Pseudopolymorphism

Polymorphism refers to the existence of a drug substance in multiple crystalline forms, known as polymorphs. Recently, this term has been expanded to include solvates (forms containing a solvent), amorphous forms (non-crystalline forms), and desolvated solvates (forms from which the solvent has been removed).
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