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在手术中进行微透析的方法和分析考虑

Cecile Riviere-Cazaux1, Karishma Rajani1, Masum Rahman1

  • 1Department of Neurological Surgery, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.

Fluids and barriers of the CNS
|December 20, 2023
PubMed
概括

使用高分子量导管的手术内微透析成功地采样了脑瘤患者的脑瘤微环境. 这种技术可以在手术期间实时检测代谢物和药物.

关键词:
质瘤是一种质瘤.IDH IDH 是一个字母.质谱测量质量谱测量代谢学 代谢学 代谢学微透析是一种微透析.药物动力学 药物动力学

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Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
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