脂肪组织,非传染性疾病和身体炼:一个不完美的三角形
Francisco A Monsalve1, Fernando Delgado-López2, Barbra Fernández-Tapia3
1Department of Basic Biomedical Science, Faculty of Health Sciences, Universidad de Talca, Talca 3465548, Chile.
International journal of molecular sciences
|December 23, 2023
概括
脂肪组织功能障碍导致肥胖和相关疾病. 运动可以减少炎症,而非传染性疾病会增加炎症,这突出了肥胖管理的个性化方法.
科学领域:
- 代谢生理学 代谢生理学
- 免疫学 免疫学 免疫学
- 内分泌学 在内分泌学.
背景情况:
- 脂肪组织对于能量恒温,内分泌,免疫和神经调节功能至关重要.
- 功能失调的脂肪组织分泌促炎性脂肪基因,导致代谢疾病,心血管问题和癌症.
- 肥胖管理通常侧重于饮食和运动,但个人的反应各不相同.
研究的目的:
- 审查肥胖的病理生理机制.
- 检查脂肪组织,运动和非传染性疾病之间的相互作用,以维持身体的平衡.
- 探索针对肥胖的个性化诊断和治疗策略.
主要方法:
- 关于肥胖病理生理机制的文献综述.
- 分析脂肪组织,运动和非传染性疾病的作用.
- 讨论诊断变量,包括分子概况,生活方式,健康状况和微生物群.
主要成果:
- 运动通常会降低促炎性标志物.
- 非传染性疾病与慢性炎症的增加有关.
- 对运动和疾病相互作用的个体反应是异质的.
结论:
- 肥胖病原包括脂肪组织,生活方式和疾病之间的复杂相互作用.
- 考虑到分子形状,生活方式和微生物组的个性化诊断至关重要.
- 奥米克斯方法和精准医学有望改善肥胖的诊断和治疗.
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