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相关概念视频

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

689
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
689

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相关实验视频

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Genetic Modification and Recombination of Salivary Gland Organ Cultures
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唾液腺生物工程 唾液腺生物工程

Stephen C Rose1, Melinda Larsen2, Yubing Xie1

  • 1Department of Nanoscale Science and Engineering, College of Nanotechnology, Science, and Engineering, University at Albany, SUNY, 257 Fuller Road, Albany, NY 12203, USA.

Bioengineering (Basel, Switzerland)
|January 22, 2024
PubMed
概括

唾液腺组织工程为数百万患有功能障碍的人提供了一个有希望的解决方案. 研究探讨了细胞,生物材料和创新的策略,以恢复唾液腺功能.

关键词:
这是一种有机物质的有机物质.复兴再生是一种再生方式.唾液腺 唾液腺 是一种组织工程是组织工程.

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Preparation of Murine Submandibular Salivary Gland for Upright Intravital Microscopy
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Last Updated: Jul 5, 2025

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科学领域:

  • 再生医学是一种再生医学.
  • 生物材料科学 生物材料科学
  • 细胞生物学 细胞生物学

背景情况:

  • 唾液腺功能障碍影响全球数以百万计的人,需要新的治疗方法.
  • 了解正常的唾液腺发育以及纤维化和衰老在病理学中的作用至关重要.
  • 目前对唾液腺功能障碍的治疗方法有限,这凸显了对先进解决方案的需求.

研究的目的:

  • 审查目前的唾液腺组织工程研究格局.
  • 检查适合的细胞来源,生物材料和唾液腺再生的制造技术.
  • 评估创新的工程策略,以增强功能组织的整合.

主要方法:

  • 审查关于唾液腺发育,病理学和组织工程的现有文献.
  • 对各种细胞类型 (细胞系,初级细胞,干细胞) 进行再生应用的分析.
  • 评估生物材料,脚手架制造和先进的工程技术 (生物打印,微流体,纳米粒子).

主要成果:

  • 多种细胞类型,生物材料和制造方法显示出唾液腺组织工程的潜力.
  • 正在探索生物打印和纳米颗粒等创新策略,以改善血管化,内化和移植.
  • 在开发功能性工程唾液腺组织方面取得了重大进展.

结论:

  • 唾液腺组织工程在治疗唾液腺功能障碍方面具有相当大的前景.
  • 需要进一步的研究来优化工程组织的细胞存活,分化和功能整合.
  • 这一领域为改善患者生活质量提供了潜在的治疗途径.