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Preparation and Reactions of Sulfides02:26

Preparation and Reactions of Sulfides

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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.
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Reduction of Alkenes: Asymmetric Catalytic Hydrogenation02:17

Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

3.3K
Catalytic hydrogenation of alkenes is a transition-metal catalyzed reduction of the double bond using molecular hydrogen to give alkanes. The mode of hydrogen addition follows syn stereochemistry.
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
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Preparation and Reactions of Thiols02:33

Preparation and Reactions of Thiols

6.2K
Thiols are prepared using the hydrosulfide anion as a nucleophile in a nucleophilic substitution reaction with alkyl halides. For instance, bromobutane reacts with sodium hydrosulfide to give butanethiol.
6.2K
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

2.1K
Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists...
2.1K

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Updated: Jul 3, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
12:30

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework

Published on: April 9, 2018

9.0K

嵌入金属的充电增强型硫尿素催化剂.

Daniel R Blechschmidt1, Cal Mergendahl1, Steven R Kass1

  • 1Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, MN 55455, USA. kass@umn.edu.

Organic & biomolecular chemistry
|February 12, 2024
PubMed
概括

新的金属催化剂有效催化弗里德尔-克拉夫特化反应. 这些带正电荷的化合物,包括铁或,与中性形式相比,显示出增强的活性,使新的催化应用成为可能.

科学领域:

  • 有机金属化学 有机金属化学
  • 催化剂是一种催化剂.
  • 有机合成 有机合成

背景情况:

  • 金属盐是有着潜在的催化应用的有机金属化合物.
  • 弗里德尔-克拉夫特化是有机合成中形成碳-碳键的基本反应.

研究的目的:

  • 合成和描述新型金属衍生物作为催化剂.
  • 评估这些化合物在Friedel-Crafts化反应中的催化活性.
  • 探索易斯和布伦斯特德酸度在它们的催化性能中的作用.

主要方法:

  • 合成N-铁-N'-乙urea和N-cobaltocenium-N'-phenylthiourea衍生物. 这种化学合成的方法是:
  • 在Friedel-Crafts的催化试验中,用trans-β-nitrostyrenes对醇进行基化.
  • 化合物的表征,包括对类似物进行X射线晶体学.

主要成果:

  • 成功制备了三种金属盐 (4a,4b,5),其中含有四基-[3,5-bis(三甲) 酸 (BArF4) 的反.
  • 在Friedel-Crafts化中表现出高的催化活性,性能优于减少的中性类型.
  • 确定了双重的易斯和布伦斯特德酸性位点,使充电激活催化.

更多相关视频

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
09:37

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

Published on: October 18, 2019

9.6K
Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
08:25

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs

Published on: January 17, 2020

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相关实验视频

Last Updated: Jul 3, 2025

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
12:30

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework

Published on: April 9, 2018

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Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
09:37

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

Published on: October 18, 2019

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Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
08:25

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs

Published on: January 17, 2020

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结论:

  • 金属盐是Friedel-Crafts化过程中的有效催化剂.
  • 这些化合物的酸性和双酸性是它们增强的催化活性的关键.
  • 含有的金属硫氨酸为隔离和表征提供了卓越的稳定性.