耳水道重新检查:使用人类胎儿的组织学研究
Kwang Ho Cho1, Ji Hyun Kim2, Yohei Honkura3
1Department of Neurology, Wonkwang University School of Medicine and Hospital, Institute of Wonkwang Medical Science, Iksan, Republic of Korea.
概括
耳水道 (CA) 从脑膜组织中形成,洞穴起源于小 tympani,而不是CA. 耳静脉的发育遵循与CA不同的途径.
科学领域:
- 人体解剖学 解剖学 解剖学
- 胚胎学 胚胎学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 喉水道 (CA) 将喉的近淋巴空间连接到后脑洞的脑下沟空间.
- 了解CA的发展对于内耳研究至关重要.
研究的目的:
- 为了确定CA化是否发生在下大脑关节或耳侧.
- 在人类胎儿发育过程中调查CA及其相关静脉的生长和退化模式.
主要方法:
- 对嵌入氨酸的人类胎儿切片的组织学检查.
- 研究包括15名中期胎儿 (CRL 39-115毫米) 和12名近期胎儿 (CRL 225-328毫米).
主要成果:
- 一个介质细胞凝结,潜在的CA结合,在9-10周没有静脉出现.
- 甲状腺下突出进入CA带,在10-12周左右启动了大 tympani 腔位.
- 在近期的胎儿中,CA anlage本身没有空洞化;CA缩小并被抹去.
结论:
- 该CA起源于脑膜组织,其化是由状发育驱动的.
- 这种CA位可能代表了光喉神经分支的残余.
- 耳静脉的发育似乎独立于CA的形成.
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