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在模拟西格拉菌感染的近期进展

Sydney L Miles1, Kathryn E Holt2, Serge Mostowy1

  • 1Department of Infection Biology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

Trends in microbiology
|February 29, 2024
PubMed
概括

像器官在芯片上,斑马鱼,老鼠和人类感染模型这样的创新模型对于理解西格拉病原体和开发这种腹疾病的新疗法至关重要. 这些工具加速了新疗法和疫苗的发现.

关键词:
石格蕾拉 (Shigella) 是一种植物.动物模型动物模型流行病学流行病学主机响应的主机响应.这是先天免疫力.疫苗 疫苗 疫苗 疫苗

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Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...