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相关概念视频

The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

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同时发生的周植入炎和牙周炎是否具有共同的微生物群? 一个试点研究研究.

Ana Parga1,2, José Manuel Pose-Rodríguez3, Andrea Muras1

  • 1Department of Microbiology and Parasitology, CIBUS-Faculty of Biology, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain.

Dentistry journal
|April 26, 2024
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概括

通过比较口腔病变,这项研究在围植入炎和牙周病中发现了不同的微生物特征. 周植入炎部位显示出更高的病原体丰富度,表明相关但不同的疾病机制.

关键词:
这就是Illumina Illumina.收集方法 收集方法微生物学的微生物.口腔微生物组是口腔的微生物组.周植入体炎 (Peri-implantitis) 是一种疾病,牙周病是一种牙周病.

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科学领域:

  • 口腔微生物学 口腔微生物学
  • 牙周病学 牙周病学
  • 植入物牙科 植入物牙科

背景情况:

  • 关于周植入物和牙周病变之间的病因联系,存在相互矛盾的文献.
  • 了解微生物差异对于诊断和治疗这些口腔疾病至关重要.

研究的目的:

  • 为了比较并发的周植入物和牙周病变的微生物组成.
  • 评估样本采集方法对微生物恢复的影响.
  • 为了阐明围植入炎和牙周疾病微生物组之间的关系.

主要方法:

  • 来自9名患有并发病变的患者的微生物样本的分析.
  • 使用Illumina MiSeq对16S rRNA基因amplicon的测序.使用了Illumina MiSeq测序.
  • 采用主要组件分析用于微生物社区比较.
  • 基于采集方法的微生物数据进行了比较 (片与纸点) 和病变类型.

主要成果:

  • 纸点产生的细菌属数量较高,相比于curettes.
  • 周植入炎样本表现出比匹配的牙周样本更大的细菌多样性.
  • 牙周样本包含的操作分类单位 (OTU) 比周植入炎样本更多.
  • 特定的口腔病原体 (例如,Porphyromonas,Treponema) 在围植入炎中更为丰富.
  • 聚合菌在牙周病变中更为普遍,显示出明显的微生物特征.

结论:

  • 周植入炎和牙周病具有不同的但相关的微生物特征.
  • 研究结果表明,在周围植入物感染中存在不同的致病机制.
  • 需要使用更大的样本大小进行进一步的研究,以确认这些微生物差异.