Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Viral Mutations00:36

Viral Mutations

32.3K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
32.3K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The effect of physical exercise therapy on autism spectrum disorder:a systematic review and meta-analysis.

Psychiatry research·2024
Same author

Progress of SGLT2 inhibitors in the treatment of common immune-related nephropathies.

International urology and nephrology·2024
Same author

From electricity to vitality: the emerging use of piezoelectric materials in tissue regeneration.

Burns & trauma·2024
Same author

Removal of tetracycline in the water by a kind of S/N co-doped tea residue biochar.

Journal of environmental management·2024
Same author

Discovery of a first-in-class protein degrader for the c-ros oncogene 1 (ROS1).

Bioorganic chemistry·2024
Same author

Aptamer and Thiol Co-Regulated Color-Shifting Fluorophores via Dynamic Through-Bond/Space Conjugation for Constructing Ratiometric RNA Sensor.

Small (Weinheim an der Bergstrasse, Germany)·2024

相关实验视频

Updated: Jun 27, 2025

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

37.3K

人类病毒组研究中的十个计算挑战

Yifan Wu1, Yousong Peng1

  • 1Bioinformatics Center, College of Biology, Hunan Provincial Key Laboratory of Medical Virology, Hunan University, Changsha 410082, China.

Virologica Sinica
|May 2, 2024
PubMed
概括
此摘要是机器生成的。

了解人类病毒组正在进步,但计算工具落后. 这一观点详细介绍了十个关键的计算挑战,并为人类病毒研究提出了解决方案.

关键词:
人工智能的人工智能是人工智能.计算生物学是一种计算生物学.计算型病毒学学.人类病毒组 人类病毒组

更多相关视频

Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example
05:45

Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example

Published on: March 11, 2020

8.8K
Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

12.2K

相关实验视频

Last Updated: Jun 27, 2025

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

37.3K
Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example
05:45

Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example

Published on: March 11, 2020

8.8K
Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
09:40

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins

Published on: June 11, 2015

12.2K

科学领域:

  • 病毒学 病毒学
  • 生物信息学是一种生物信息学.
  • 计算生物学 计算生物学

背景情况:

  • 人类病毒组在健康和疾病中起着至关重要的作用.
  • 人类病毒研究受到缺乏有效的计算工具的限制.
  • 病毒基因组缺乏通用标记基因,病毒蛋白通常与已知的蛋白质具有较低的同质性.

研究的目的:

  • 系统地概述人类病毒研究中的十个计算挑战.
  • 讨论每个挑战的原因,当前进展和潜在的解决方案.
  • 为了指导人类病毒研究领域的未来计算努力.

主要方法:

  • 对计算挑战的基于视角的分析.
  • 审查现有研究和提出的解决方案.
  • 确定未来研发的关键领域.

主要成果:

  • 在人类病毒研究中发现了十个不同的计算挑战.
  • 挑战来自于病毒组多样性,缺乏通用标记物,低病毒丰度,低蛋白质同质性和动态性质.
  • 针对每个挑战,提出了潜在的解决方案和研究方向.

结论:

  • 解决这些计算挑战对于推进人类病毒研究至关重要.
  • 计算科学家和病毒学家之间的跨学科合作至关重要.
  • 这一观点为未来的病毒学计算工具开发提供了路线图.