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相关概念视频

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

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The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
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Coronary Circulation01:21

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The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
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Pathophysiology of Heart Failure01:17

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Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
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Typical heart performance is influenced by heart rate, rhythm, myocardial contraction, and metabolism or blood flow. The cardiac muscle exhibits distinct electrophysiological features, including pacemaker activity and calcium channel control, which play a vital role in the heart's response to various drugs. The autonomic nervous system, comprising the sympathetic and parasympathetic branches, regulates heart rate. Sympathetic activation increases heart rate, while parasympathetic activation...
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相关实验视频

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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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冠状动脉微血管功能障碍和心房储功能.

Julien La Mela1, Laurent Riou2, Gilles Barone-Rochette3,4,5,6

  • 1Department of Cardiology, University Hospital, Grenoble, 38000, France.

Cardiovascular ultrasound
|May 14, 2024
PubMed
概括

冠状动脉微血管功能障碍 (CMD) 与左心房压力降低 (LASr) 有关,这表明早期的扩张功能障碍. LASr可能有助于识别CMD和非阻塞冠状动脉的患者.

关键词:
冠状动脉微血管功能障碍 冠状动脉微血管功能障碍左心房的压力储是左心房的压力储.

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科学领域:

  • 心脏病学 心脏病学
  • 心血管生理学心血管生理学
  • 诊断成像 诊断成像 诊断成像

背景情况:

  • 冠状动脉微血管功能障碍 (CMD) 涉及心脏最小血管的异常,影响透缩功能.
  • 侵袭性冠状动脉生理学用于CMD诊断.
  • 左心房应变 (LASr) 在检测透缩功能障碍方面表现有前途.

研究的目的:

  • 调查冠状动脉微血管功能障碍 (CMD) 和左心房应变 (LASr) 之间的关系.
  • 评估LASr作为CMD患者早期扩张功能障碍的潜在非侵入性标志物.

主要方法:

  • 患有非阻塞冠状动脉 (NOCA) 的患者使用侵入性热稀释进行了CMD评估.
  • 左心房应变 (LASr) 通过心声回声扫描进行了非侵入性评估.
  • 进行了相关性和回归分析,以确定CMD和LASr之间的关联.

主要成果:

  • 42名患者中有26名患有心血管疾病;与没有心血管疾病的患者相比,心血管疾病患者 (24.6%±6.1%) 的 LASr 显著较低 (30.3%±7.8%).
  • 在冠状动脉流量储备和LASr (r=0.47,p=0.002) 之间发现了适度的相关性.
  • CMD与LASr独立相关 (OR=0.88,p=0.04),LASr的切断值为25.5%,识别了患有CMD的患者.

结论:

  • 患有NOCA和CMD的患者显著减少了LASr.
  • 降低的LASr表明CMD患者的扩张功能早期受损.
  • 拉斯尔可以作为一个有价值的非侵入性指标,用于检测CMD的透析功能障碍.