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相关概念视频

Development of the Heart01:27

Development of the Heart

919
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
919
Development of Blood Vessels01:07

Development of Blood Vessels

567
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
567
Chambers of the Heart01:16

Chambers of the Heart

4.4K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
4.4K

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相关实验视频

Updated: Jun 23, 2025

Generating Self-Assembling Human Heart Organoids Derived from Pluripotent Stem Cells
08:56

Generating Self-Assembling Human Heart Organoids Derived from Pluripotent Stem Cells

Published on: September 15, 2021

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人类心脏发育的发展

Jill P J M Hikspoors1, Nutmethee Kruepunga2,3, Greet M C Mommen2

  • 1Department of Anatomy & Embryology, Maastricht University, Maastricht, The Netherlands. jill.hikspoors@maastrichtuniversity.nl.

Advances in experimental medicine and biology
|June 17, 2024
PubMed
概括
此摘要是机器生成的。

这项研究使用3D模型重建了人类心脏发育的3.5到8周. 它详细介绍了心脏结构的形成和隔离,为胚胎心脏发育提供了时间表.

关键词:
心脏隔间是心脏的隔间.一个心脏循环.心脏隔断是因为心脏的隔断.发展时间表的发展时间表.胚胎心室 胚胎心室增长的增长 增长的增长进行分期,分期.

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Analysis of Cardiac Chamber Development During Mouse Embryogenesis Using Whole Mount Epifluorescence
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Analysis of Cardiac Chamber Development During Mouse Embryogenesis Using Whole Mount Epifluorescence

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High Efficiency Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes and Characterization by Flow Cytometry
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High Efficiency Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes and Characterization by Flow Cytometry

Published on: September 23, 2014

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相关实验视频

Last Updated: Jun 23, 2025

Generating Self-Assembling Human Heart Organoids Derived from Pluripotent Stem Cells
08:56

Generating Self-Assembling Human Heart Organoids Derived from Pluripotent Stem Cells

Published on: September 15, 2021

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Analysis of Cardiac Chamber Development During Mouse Embryogenesis Using Whole Mount Epifluorescence
06:27

Analysis of Cardiac Chamber Development During Mouse Embryogenesis Using Whole Mount Epifluorescence

Published on: April 17, 2019

7.6K
High Efficiency Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes and Characterization by Flow Cytometry
13:13

High Efficiency Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes and Characterization by Flow Cytometry

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科学领域:

  • 发育生物学是发展生物学.
  • 胚胎学 胚胎学
  • 心血管科学 心血管科学

背景情况:

  • 人类心脏发育是一个复杂的过程,需要3D可视化.
  • 以前的综合性原料缺乏早期胚胎阶段的详细3D重建.

研究的目的:

  • 为了创建一个详细的3D地图集的人类胚胎心脏发育3.5到8周.
  • 描述大约70个心脏结构的顺序形成和重塑.

主要方法:

  • 来自12个人类胚胎 (3.5-8周) 的组织学切片的细分.
  • 为可视化创建交互式,校准的3D PDF模型.
  • 跨卡内基阶段的心脏结构发展和重塑的增量描述.

主要成果:

  • 详细的心脏管的形成时间表,循环,区间的发展和隔离 (卡内基阶段9-20).
  • 描述了外流通道和动脉极的主要改造事件.
  • 在胚胎年龄,小鼠发育和卡内基阶段之间提供了定量相关性.

结论:

  • 这项研究为了解早期人类心脏形态发生提供了全面的3D资源.
  • 建立了胚胎心脏发育中的关键事件的详细时间框架.
  • 提供了对发育时间和物种间相关性变化的见解.