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结石导致的功能衰竭:一项ANZDATA研究
Hicham Cheikh Hassan1,2, David J Tunnicliffe3,4, Lyn Loyd5
1Graduate School of Medicine, University of Wollongong, Wollongong, New South Wales, Australia.
概括
导致衰竭 (KF) 的结石并不常见,但需要置换疗法 (KRT) 的患者在透析时的生存率更好. 由于结石与其他原因造成的KF患者的移植结果相似.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 结石是一种常见的疾病,发病率越来越高.
- 结石对衰竭 (KF) 和替代疗法 (KRT) 的影响尚不清楚.
- 这项研究调查了由结石引起的KF的发生率和结果.
研究的目的:
- 为了确定结石导致的衰竭 (KF) 的发生率.
- 为了比较接受脏替代疗法 (KRT) 治疗结石的患者与其他原因的结果.
- 分析移植患者的患者存活率和移植存活率.
主要方法:
- 研究了从澳大利亚和新西兰透析和移植 (ANZDATA) 登记处在1981-2020年间开始KRT的成年患者.
- 由于结石导致的KRT患者与其他原因的患者进行了比较.
- 考克斯回归模型分析了患者存活率,透析结果和移植移植的存活率.
主要成果:
- 834名患者 (1.1%) 由于结石而开始KRT;发病率稳定在每百万人口每年1.17%.
- 针对结石进行透析的患者的存活率 (HR 0.89) 与没有结石的患者相比较高.
- 患有结石的脏移植接受者有更长的移植时间,但死亡率和移植损失率相似.
结论:
- 在研究期间,由于结石造成的功能衰竭的发生率保持稳定.
- 患有结石且需要脏替代疗法的患者在透析时的生存率更高.
- 在结石和非结石组之间,移植结果是可比的.
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