快速感官适应的多个不同的时间尺度在thalamocortical电路中.
Yi Juin Liew1,2, Elaida D Dimwamwa1, Nathaniel C Wright1
1Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.
bioRxiv : the preprint server for biology
|June 19, 2024
概括
神经适应通过改变神经信号传递在质体和皮质的不同时间尺度上来塑造感官感知. 这个过程将感官编码从检测转移到歧视.
科学领域:
- 神经科学是一个神经科学.
- 感官处理 感官处理
- 神经适应 神经适应
背景情况:
- 神经元的表现是动态的,受到感官输入的影响.
- 神经信号的快速适应对于感知至关重要,但人们对其了解甚少.
研究的目的:
- 研究跨多个时间尺度 (毫秒到秒) 的快速适应.
- 检查体 (VPm) 和主要体感皮质 (S1) 的腹中后中核的适应性.
主要方法:
- 在麻醉小鼠中,从VPm和S1同时进行多电极记录.
- 控制的持续的胡须刺激.
- 对VPm的光遗传激活.
主要成果:
- 确定了两种不同的时间表,即火速的快速适应和VPm和S1.1中的同步.
- thalamocortical突触疗效显示适应性. 这是一个很好的例子.
- 在S1中,较长时间的适应与乳头火速和同步变化有关.
结论:
- 适应通过不同的时间动态通过感官路径进行.
- 适应将感官编码策略从检测转变为歧视.
- 多种机制有助于快速适应,支持传感处理的统一框架.
相关概念视频
Integration of Synaptic Events
1.5K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...
1.5K
Neural Circuits
1.1K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
1.1K


