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Updated: Jun 21, 2025

Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells
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Author Spotlight: Evaluation of Protein-Condensate Dynamics in Live Human Cells

Published on: January 5, 2024

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整体膜蛋白质动力学和功能单分子成像

Arnab Modak1, Zeliha Kilic1, Kanokporn Chattrakun1

  • 1Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; email: arnab.modak@stjude.org, zeliha.kilic@stjude.org, kanokporn.chattrakun@stjude.org, daniel.terry@stjude.org, ravi.kalathur@stjude.org, scott.blanchard@stjude.org.

Annual review of biophysics
|July 16, 2024
PubMed
概括

单分子FRET (smFRET) 推进了整体膜蛋白 (IMP) 的研究,揭示了细胞功能和药物开发至关重要的短暂状态. 这种方法有助于理解IMP的结构和作用机制.

关键词:
光共振能量转移的能量转移.遗传密码扩张 扩张整体膜蛋白质的整体膜蛋白质.本质上是动态的系统.超稳定的能源格局.单个分子成像技术

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