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Updated: May 3, 2026

Single-cell Profiling of Developing and Mature Retinal Neurons
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scSemiProfiler:通过使用深度生成模型和主动学习进行半分析来推进大规模单细胞研究

Jingtao Wang1,2, Gregory J Fonseca1,2,3, Jun Ding4,5,6,7,8

  • 1Meakins-Christe Laboratories, Research Institute of McGill University Health Centre, 1001 Decarie Blvd, Montreal, H4A 3J1, Quebec, Canada.

Nature communications
|July 16, 2024
PubMed
概括

scSemiProfiler通过集成批量和有限的单细胞测序数据,为单细胞分析提供了具有成本效益的解决方案. 这种计算框架可以在大型生物医学研究中进行详细的细胞分析,克服成本障碍.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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