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The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
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相关实验视频

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在海湾战争时期的退伍军人中,缺口积累的特征

S E Petry1, A D Thompson, E R Hauser

  • 1Sarah E. Petry, University of North Carolina, Chapel Hill, USA, spetry@email.unc.edu.

The Journal of frailty & aging
|July 31, 2024
PubMed
概括

海湾战争疾病 (GWI) 加快了退伍军人的衰老. 严重的GWI (SGWI+) 显著增加了累积健康缺陷的风险,影响中年人最深刻.

关键词:
财政赤字累积 财政赤字累积 财政赤字累积衰老的衰老 衰老的衰老疾病负担 疾病负担生命表中的生命表.

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科学领域:

  • 老年学是一门学科.
  • 退伍军人健康 退伍军人的健康
  • 流行病学 流行病学

背景情况:

  • 第一次海湾战争 (1990-1991) 的退伍军人正在衰老,许多人患有海湾战争疾病 (GWI),这是一种慢性多症状疾病.
  • GWI是一个复杂的疾病,影响退伍军人的健康和生物年龄,因为他们达到中年和老年成人.

研究的目的:

  • 分析严重GWI (SGWI+) 的退伍军人与没有 (SGWI-) 的退伍军人的赤字积累.
  • 评估医学上无法解释的疾病,如GWI和加速衰老之间的关系.

主要方法:

  • 追溯队列设计,利用来自10,042名海湾战争时代退伍军人的准纵向数据.
  • 从1991-2013年使用赤字积累指数 (DAI) 分析了来自海湾战争时代队列生物存储库 (GWECB) 的1,054名参与者.
  • 基于CDC病例定义的SGWI+和SGWI-组之间的赤字累积比较.

主要成果:

  • 预计大多数退伍军人将花费更多的时间在中度至实质性的健康缺陷下.
  • 有SGWI+的退伍军人积累了比SGWI-退伍军人更多的实质性赤字.
  • 中年退伍军人 (35-65岁) 经历了更长时间的实质性赤字;SGWI+个体积累赤字的风险是13倍.

结论:

  • 严重的GWI (SGWI+) 与加速衰老有关,即使在中年退伍军人中,也会增加赤字积累.
  • 医疗保健提供者应该认识到多症状疾病是加速衰老的指标.
  • 建议针对针对整体患者需求的量身定制治疗方案适用于患有GWI的退伍军人.