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Updated: Jun 17, 2025

A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
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A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells

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瘤分泌的细胞外囊泡通过触发炎性介质干细胞发育来抵消治疗反应

Crescenzo Massaro1,2, Hilal N Sensoy1, Manon Mulders1

  • 1Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Clinical cancer research : an official journal of the American Association for Cancer Research
|August 8, 2024
PubMed
概括

癌症细胞外囊泡 (EVs) 诱导炎症性介质干细胞 (iMSCs),在骨癌中驱动治疗阻力. 针对EV激活通路的组合疗法提供了一个有希望的策略来克服这种抵抗.

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