皮肤表面显微镜图像中的语义细分与文物删除
Aneesh R P1, Joseph Zacharias1
1College of Engineering Trivandrum, APJ Abdul Kalam Technological University Kerala, Thiruvananthapuram, Kerala, India.
Computers in biology and medicine
|August 17, 2024
概括
删除头发和黑暗角落等文物显著改善了皮肤病变细分的深度学习模型,提高了皮肤镜图像的诊断准确性.
科学领域:
- 皮肤病学和医学成像学
- 医疗保健中的人工智能
背景情况:
- 皮肤表面显微镜,包括皮肤显微镜,对于诊断皮肤病变和减少不必要的活检至关重要.
- 皮肤病变的准确细分对于分类至关重要,但皮肤透视图像中的文物构成了重大挑战.
研究的目的:
- 分析皮肤表面显微镜图像中的常见工件及其对深度学习细分模型的影响.
- 调查黑角检测和去除的新方法,以改善皮肤病变细分.
主要方法:
- 在皮肤镜像中分析常见的文物,特别是头发和黑暗的角落.
- 在使用PH2,ISIC 2017和ISIC 2018数据集去除文物之前和之后对深度学习模型性能的评估.
- 使用文物表面密度和子系数评估细分性能.
主要成果:
- 头发和黑暗的角落被确定为影响细分精度的普遍工件.
- 删除文物导致数据集中的子系数得到了大幅改善:PH2的93.49 (86.81),ISIC 2017的85.86 (79.91),ISIC 2018的75.38 (51.28) 等.
- 这项研究强调了人工物清除在增强皮肤病变细分的深度学习有效性方面的关键作用.
结论:
- 移除文物对于优化基于深度学习的皮肤病变细分至关重要.
- 提出的检测和去除毛发和暗角的方法显著提高了细分性能.
- 改进的细分精度有可能提高色素皮肤病变的临床诊断性能.
相关概念视频
Imaging Biological Samples with Optical Microscopy
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
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In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
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The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
Three-Dimensional Microscopy in Microbiology
Three-dimensional imaging techniques are essential in cell biology, allowing researchers to visualize intricate cellular structures with high resolution. Two prominent methods, Differential Interference Contrast Microscopy (DIC) and Confocal Scanning Laser Microscopy (CSLM), provide distinct advantages for imaging live and thick specimens, respectively.Differential Interference Contrast MicroscopyDIC microscopy enhances contrast in transparent, unstained samples by converting phase...


