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减少听觉语言幻觉的痛苦:一个多中心,并行,单盲,随机控制可行性试验的相关疗法
Tania Marie Lincoln1, Björn Schlier1,2, Rebecca Müller1
1Clinical Psychology and Psychotherapy, Institute of Psychology, Faculty of Psychology and Human Movement Science, Universität Hamburg, Hamburg, Germany.
Psychotherapy and psychosomatics
|August 21, 2024
概括
添加到通常治疗 (TAU) 的相关疗法 (RT) 是一种可行的和安全的干预措施,用于减少听觉语言幻觉 (AVH) 的痛苦. 这项研究支持对RT的进一步测试.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 听觉语言幻觉 (AVHs) 对精神分裂症谱系障碍患者造成重大痛苦.
- 目前的治疗方法往往侧重于减轻症状,但痛苦与个体与AVHs的关系有关.
研究的目的:
- 评估随机对照试验 (RCT) 对"相关疗法" (RT) 与通常治疗 (TAU) 结合的可行性.
- 确定RT + TAU是否优于TAU单独在减少与AVHs相关的痛苦方面.
主要方法:
- 一个多中心,单盲,随机控制的可行性试验,涉及177名持久,痛苦的AVH和精神分裂症谱系障碍的参与者.
- 参与者接受了RT + TAU或TAU单独,在基线,5个月和9个月进行评估.
- 可行性结果包括招聘,留住,安全和治疗师坚持,AVH痛苦作为主要终点.
主要成果:
- 该研究证明了极好的可行性,在9个月内保持87%和高治疗师坚持 (98%).
- 没有报告任何严重的不良反应,这表明了有利的安全性.
- 与TAU单独相比,RT + TAU显示了与AVH痛苦减少的非显著趋势.
结论:
- 随机对照试验调查相关疗法是可行的,安全的,并得到了参与者的良好接受.
- 这些发现为进行最终试验提供了坚实的基础,以确认RT在减少AVH痛苦方面的有效性.
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