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Updated: May 10, 2026

An Analytical Tool that Quantifies Cellular Morphology Changes from Three-dimensional Fluorescence Images
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评估2D和3D细胞环境中的药物摄入和反应差异,使用刺激拉曼散射显微镜.

Fiona Xi Xu1, Rui Sun1, Ryan Owens1

  • 1Department of Chemistry, University of Washington, Seattle, Washington 98195, United States.

Analytical chemistry
|August 26, 2024
PubMed
概括

三维 (3D) 细胞培养显示出比二维培养更高的抗癌药物耐药性. 刺激拉曼散射 (SRS) 显微镜揭示了类似的细胞内药物水平,但在3D模型中减少了生长影响,表明药物耐受性增强.

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