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Updated: Jun 13, 2025

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability
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Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability

Published on: April 2, 2015

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一个pH取决于无序蛋白质的粗粒度模型:基因相互作用调节合规组合.

Rivka Calinsky1, Yaakov Levy1

  • 1Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

The journal of physical chemistry letters
|September 9, 2024
PubMed
概括

由于其中性 (His0) 和充电 (His+) 状态,在无序蛋白质中建模histidine (His) 是具有挑战性的. 我们的新模型准确地捕捉了这些状态,揭示了高pH下蛋白质紧缩的关键His0相互作用.

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