脑部状态的瞬间变化会在整个发育过程中发生变化,并导致执行功能的个体差异
Jean Ye1, Link Tejavibulya1, Wei Dai2
1Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut.
bioRxiv : the preprint server for biology
|September 24, 2024
概括
大脑信号的神经变异性 (SEV) 在发育过程中发生变化,在青春期稳定. 大脑状态参与中的这种发育转变预测了年轻人的执行功能.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 计算神经科学是一种神经科学.
背景情况:
- 神经的可变性支持灵活的大脑响应不断变化的需求.
- 从童年到青春期的大脑发育涉及经验和神经功能的显著变化.
- 了解大脑状态参与的变化在发育过程中如何演变至关重要,但仍未得到充分探索.
研究的目的:
- 调查整个童年和青春期的状态参与变化 (SEV) 的发展轨迹.
- 确定SEV变化是否预测年轻人的认知能力,特别是执行功能 (EF).
- 在SEV的发展模式中识别潜在的性别差异.
主要方法:
- 利用一种新的计算框架,同时评估多个大脑状态.
- 分析了来自3000多名参与者的横截面和纵向神经影像数据集.
- 在一个独立的青年队伍中,研究了发育性SEV模式和执行职能表现之间的关系.
主要成果:
- 在不同数据集中确定了SEV与年龄相关的变化的一致模式.
- 发现SEV发育轨迹倾向于在青春期中期左右稳定,根据性别和特定大脑状态的变化.
- 证明SEV显著预测执行职能,变化的SEV发展与较差的EF结果有关.
结论:
- 国家参与变化 (SEV) 在整个发育过程中经历了显著的变化,最终在青春期稳定.
- 在SEV的发展变化与年轻人的执行功能能力有关.
- 在发育过程中,SEV代表了一个关键的神经机制,它是认知灵活性和适应的基础.
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